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Updated: Sep 20, 2025

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
Published on: July 16, 2014
Bilateral pallidal DBS for blepharospasm: A case report and review of the literature
Joshua Lucas1, Dorian Kusyk2, Donald Whiting2
1MD Program, Drexel University College of Medicine, Philadelphia.
Background:
Deep brain stimulation (DBS) of the globus pallidus internus (GPi) in the treatment of craniocervical dystonia often requires an extended period of stimulation parameter manipulations.
Case Description:
We present a patient suffering from debilitating blepharospasm treated with bilateral DBS of the GPi alongside 7 years of stimulation parameter manipulations and a literature review of comparable patients.
Conclusion:
Our literature review suggests that a patient's specific dystonic symptoms can guide stimulation parameter manipulations. Further research regarding trends in stimulation parameters being used in the field for different dystonic symptoms may expedite the stimulation parameter manipulation process.

