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Related Concept Videos

Esophagus01:24

Esophagus

1.4K
The esophagus, a muscular conduit linking the pharynx and stomach, measures roughly 10 inches (25.4 cm) and sits behind the trachea. It remains collapsed when not swallowing. The esophagus follows a predominantly straight path through the thoracic mediastinum and enters the abdominal cavity through a diaphragmatic opening known as the esophageal hiatus.
The movement of edibles from the pharynx into the esophagus is facilitated by the upper esophageal sphincter, which is formed primarily by the...
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Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

284
Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
284
Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

325
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
325
Barrett Esophagus-I: Introduction01:21

Barrett Esophagus-I: Introduction

226
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
226
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

170
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
170
Esophageal Varices-I: Introduction01:24

Esophageal Varices-I: Introduction

367
Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
367

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Related Experiment Video

Updated: Sep 20, 2025

Isolation of Myofibroblasts from Mouse and Human Esophagus
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Esophageal spindle cell lipoma.

José Fernando Val-Bernal1, Marta María Mayorga, Natalia Fontanil

  • 1Pathology Unit, Department of Medical and Surgical Sciences, University of Cantabria, Santander, Spain; fernando.val@unican.es.

Romanian Journal of Morphology and Embryology = Revue Roumaine De Morphologie Et Embryologie
|June 8, 2022
PubMed
Summary

Spindle cell lipomas (SCLs) are rare esophageal tumors. This case highlights the endoscopic removal of a pedunculated SCL, emphasizing accurate diagnosis and treatment for symptomatic patients.

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Area of Science:

  • Gastroenterology
  • Surgical Pathology

Background:

  • Esophageal lipomas are uncommon benign tumors.
  • Spindle cell lipomas (SCLs) are a rare subtype, with esophageal SCLs being exceptionally infrequent.

Observation:

  • A 62-year-old woman presented with chronic heartburn and abdominal distension.
  • Imaging revealed a middle esophageal lipomatous polypoid mass.
  • The lesion was successfully excised endoscopically.

Findings:

  • Histopathology confirmed the mass as a pedunculated spindle cell lipoma (SCL).
  • The resected lesion measured 3.5×2×1 cm.

Implications:

  • Accurate diagnosis of esophageal SCL is vital to differentiate from malignant neoplasms.
  • Endoscopic excision is the recommended treatment for symptomatic esophageal SCLs.
  • This case expands the known spectrum of lipomatous tumors affecting the esophagus.