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Changes in umbilical catheters' microstructure in vivo: A prospective study
Alina Sobczak1, Aleksandra Kowalik1, Marta Homa2
1Department of Pediatrics, Jagiellonian University Medical College, Kraków, Poland.
The Journal of Vascular Access
|June 8, 2022
Summary
Umbilical catheters can develop thrombosis and bacterial colonization, especially in premature infants. Increased monitoring of these devices is crucial for neonatal care.
Area of Science:
- Neonatal intensive care
- Medical device analysis
- Neonatal physiology
Background:
- Umbilical vessels provide central venous and arterial access for neonates.
- Catheterization complications can be misdiagnosed as prematurity complications.
Purpose of the Study:
- To investigate in vivo changes in umbilical catheters.
- To assess the clinical significance of catheter alterations.
Main Methods:
- Prospective observational study of 41 polyurethane umbilical catheters (venous and arterial).
- Utilized bedside ultrasound, microbiological, and microstructural analysis.
- Included chemical analysis (energy dispersive spectroscopy) and scanning electron microscopy.
Main Results:
- Higher rates of thrombosis (31%) and bacterial colonization (8%) in umbilical venous catheters compared to arterial.
- Thrombosis and colonization inversely correlated with gestational age.
- Calcium deposition observed on catheters; external coating formed within hours.
Conclusions:
- Umbilical catheter in vivo changes are complex and clinically significant.
- Increased bedside monitoring of indwelling umbilical catheters is recommended.
