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Strategies for Assessing Autistic-Like Behaviors in Mice
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Autistic traits in trichotillomania.

Jon E Grant1, Samuel R Chamberlain2,3

  • 1Department of Psychiatry & Behavioral Neuroscience, University of Chicago, Pritzker School of Medicine, Chicago, Illinois, USA.

Brain and Behavior
|June 8, 2022
PubMed
Summary

Adults with trichotillomania (TTM) show higher rates of autistic traits. This suggests a need to screen for autism spectrum disorder (ASD) in TTM patients, though its impact on treatment is unknown.

Keywords:
autismimpulsivityobsessive-compulsive disorders

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Area of Science:

  • Psychiatry
  • Psychology
  • Neurodevelopmental Disorders

Background:

  • Trichotillomania (TTM) is characterized by hair pulling, with limited research on social interaction deficits.
  • Similarities exist between TTM behaviors and stereotypies observed in autism spectrum disorders (ASD).

Purpose of the Study:

  • To investigate the prevalence of autistic traits in adults diagnosed with TTM.
  • To explore the relationship between autistic traits and other clinical variables in TTM.

Main Methods:

  • Fifty adults with DSM-5 TTM completed diagnostic interviews and symptom inventories.
  • Autistic traits were assessed using the Brief Autism-Spectrum Quotient (AQ-10) screening tool.

Main Results:

  • The study included 50 participants (86% female, mean age 30.2 years).
  • 14.6% of participants scored 6 or higher on the AQ-10, indicating elevated autistic traits.
  • Autism scores correlated with family dysfunction but not TTM symptom severity or impulsivity.

Conclusions:

  • Adults with TTM exhibit a higher prevalence of probable ASD based on self-report screening.
  • Screening for autistic traits in TTM patients is recommended.
  • The influence of autistic traits on TTM treatment outcomes requires further investigation.