In-Hospital Mortality from Cardiovascular Diseases in Brazil during the First Year of The COVID-19 Pandemic
Anderson da Costa Armstrong1, Lucas Gomes Santos2, Thiago Cavalcanti Leal2
1Universidade Federal do Vale do São Francisco, Petrolina, PE - Brasil.
Insights
The COVID-19 pandemic impacted cardiovascular disease (CVD) mortality in Brazil. While overall CVD deaths decreased slightly in 2020, Brazil experienced a 13.3% excess in-hospital mortality, with regional variations.
Area of Science:
- Public Health
- Epidemiology
- Cardiovascular Medicine
Background:
- The COVID-19 pandemic has significantly influenced global mortality patterns, particularly for cardiovascular diseases (CVD).
- Brazil's vast size and healthcare disparities necessitate localized analysis of health impacts.
Purpose of the Study:
- To assess in-hospital mortality trends for cardiovascular diseases (CVD) within Brazil's public health system.
- To analyze the impact of the COVID-19 pandemic's first year (2020) on CVD mortality across Brazil.
Main Methods:
- Ecological study design utilizing national hospital data from Brazil's Ministry of Health.
- Analysis of absolute in-hospital deaths and mortality rates at national, regional, and state levels.
- Application of the P-score, adjusted by joinpoint regression, to quantify excess mortality compared to expected values.
Main Results:
- Brazil recorded 93,104 in-hospital CVD deaths in 2020, a figure 1.58% lower than expected, but with a 13.3% excess mortality nationwide.
- The Central-West region experienced a 15.1% increase in CVD deaths, and ten states reported higher-than-expected mortality.
- All macro-regions exhibited excess in-hospital mortality, indicating widespread pandemic-related disruption.
Conclusions:
- Brazil observed a paradoxical trend of decreased absolute in-hospital CVD deaths alongside increased in-hospital mortality rates in 2020.
- The findings highlight the complex and varied impact of the COVID-19 pandemic on cardiovascular health outcomes in Brazil.
Background:
The COVID-19 pandemic has had an impact on mortality from several diseases worldwide, especially cardiovascular diseases (CVD). Brazil is a continent-sized country with significant differences in the health care structure between its federative units.
Objective:
Analyze in-hospital mortality from CVDs in the Brazilian public health system during the first year of the COVID-19 pandemic (2020).
Methods:
This is an ecological study analyzing the absolute number of in-hospital deaths and the rate of in-hospital mortality in Brazil, its macro-regions, and federative units. Data were obtained from the Hospital Information System of the Brazilian Ministry of Health. To analyze excess mortality, the P-score was used. It compares the events observed with those expected for a given place and period. The P-score was corrected by the joinpoint regression model, with a 95% confidence interval and 5% significance level.
Results:
There were 93,104 in-hospital deaths due to CVD in Brazil in 2020, representing 1,495 fewer deaths (P score: -1.58) than expected. The central-west region had a positive P-score, with a 15.1% increase in the number of deaths. Ten federative units showed a greater number of deaths in 2020. There was also a 13.3% excess in-hospital mortality at the country level, and an excess in-hospital mortality in all macro-regions.
Conclusions:
There was a decrease in the absolute number of in-hospital deaths, as well as an increase in in-hospital mortality from CVD in Brazil, in 2020, after the COVID-19 pandemic onset.
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