Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Factors Affecting Pulmonary Ventilation

Factors Affecting Pulmonary Ventilation

Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...

Mechanical Ventilation II: Invasive Ventilation

Mechanical Ventilation II: Invasive Ventilation

Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...

Mechanical Ventilation I: Indication and Settings

Mechanical Ventilation I: Indication and Settings

Mechanical ventilation is a life-saving technique for managing acute respiratory failure and other respiratory complications. The process involves using a machine known as a ventilator to supply oxygen to the lungs and assist in removing carbon dioxide. It serves as a bridge to long-term mechanical ventilation or a temporary measure until ventilatory support is discontinued. The ventilator can maintain this function for a prolonged period, providing critical support for patients until they can...

Free Jet

Free Jet

Free jets describe the flow of liquid exiting a reservoir through an opening into the atmosphere without resistance. The velocity (v) of the liquid jet is derived using Bernoulli's principle and expressed as:

Mechanical Ventilation III: Noninvasive Ventilation

Mechanical Ventilation III: Noninvasive Ventilation

Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation...

Pulmonary Ventilation: Inhalation

Pulmonary Ventilation: Inhalation

Pulmonary ventilation is a vital process that ensures the exchange of oxygen and carbon dioxide in the lungs. It refers to the movement of air into and out of the lungs, enabling the body to obtain oxygen and remove waste carbon dioxide. In this article, we will explore the intricacies of pulmonary ventilation, including its underlying principles, mechanisms, and the interplay of pressures within the respiratory system.
Boyle's law becomes particularly pertinent when examining respiratory...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Cumulative Cytological Assessment of Repeated Non-Diagnostic Thyroid Fine Needle Aspirations: A Novel Approach to Reduce Diagnostic Uncertainty.

Diagnostic cytopathology·2026

Same author

Association Between Thyroid Gland Volume and Postoperative Hypothyroidism Following Hemithyroidectomy.

OTO open·2026

Same author

Rhinoplasty and the 'Big Five' Model: The Impact of Patients' Personality Traits on Post-surgical Satisfaction Outcomes.

Aesthetic plastic surgery·2025

Same author

Patients' obesity is linked to prolonged thyroidectomy operative time.

Langenbeck's archives of surgery·2025

Same author

Hypothyroidism After Hemithyroidectomy: A Retrospective Analysis of Temporal Trends and Key Risk Factors.

Journal of clinical medicine·2025

Same author

Completion Thyroidectomy Trends and Rates: A Systematic Review and Meta-Analysis.

Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·2024

Search research articles

Related Experiment Video

Updated: Sep 20, 2025

Evaluating Regional Pulmonary Deposition using Patient-Specific 3D Printed Lung Models

Evaluating Regional Pulmonary Deposition using Patient-Specific 3D Printed Lung Models

Published on: November 11, 2020

Parameters of high-frequency jet ventilation using a mechanical lung model.

Evgeni Kukuev¹, Evgeny Belugin¹, Dafna Willner¹

¹Departments of Anaesthesiology, Galilee Medical Centre affiliated with Azrieli Faculty of Medicine, Bar Ilan University, Safed, Israel.

Journal of Medical Engineering & Technology

|June 8, 2022

Summary

High-frequency jet ventilation (HFJV) affects respiratory mechanics differently than conventional ventilation. Studies show HFJV impacts minute ventilation, respiratory rate, and volumes, with further research needed for patient application.

Keywords:

High-frequency jet ventilation inspiratory to expiratory ratio lung compliance lung model minute volume respiratory rate tidal volume

More Related Videos

Ex Vivo Porcine Experimental Model for Studying and Teaching Lung Mechanics

Ex Vivo Porcine Experimental Model for Studying and Teaching Lung Mechanics

Published on: April 19, 2024

A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways

A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways

Published on: May 9, 2016

Related Experiment Videos

Last Updated: Sep 20, 2025

Evaluating Regional Pulmonary Deposition using Patient-Specific 3D Printed Lung Models

Evaluating Regional Pulmonary Deposition using Patient-Specific 3D Printed Lung Models

Published on: November 11, 2020

Ex Vivo Porcine Experimental Model for Studying and Teaching Lung Mechanics

Ex Vivo Porcine Experimental Model for Studying and Teaching Lung Mechanics

Published on: April 19, 2024

A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways

A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways

Published on: May 9, 2016

Area of Science:

Mechanical Ventilation
Respiratory Physiology

Background:

High-frequency jet ventilation (HFJV) is a specialized mechanical ventilation technique.
Understanding HFJV's impact on respiratory parameters is crucial for clinical application.

Purpose of the Study:

To investigate the effects of HFJV on respiratory parameters in a simulated intubated patient model.
To analyze the influence of varying respiratory rates, I:E ratios, and inspiratory pressures on ventilation across different lung compliances.

Main Methods:

Utilized a high-frequency jet ventilator connected to a ventilation monitor.
Simulated an intubated patient with varying lung compliances.
Systematically altered respiratory rate, I:E ratio, and inspiratory pressure.

Main Results:

Observed a reduction in minute ventilation with an increased respiratory rate.
Noted low airway pressures across all tested lung compliances.
Found tidal and minute volumes directly correlated with inspiratory pressure.

Conclusions:

Respiratory mechanics under HFJV differ significantly from conventional ventilation in a lung model.
Further in-vivo studies are necessary to evaluate pCO2 and end-tidal CO2 during HFJV.