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Microbial Nutrition01:28

Microbial Nutrition

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Organisms exhibit remarkable metabolic diversity, categorized based on how they acquire energy and carbon. These strategies enable survival in various ecological niches and are essential for maintaining energy flow and nutrient cycling within ecosystems.Energy and Carbon SourcesOrganisms are classified as phototrophs or chemotrophs based on energy acquisition. Phototrophs use light as their energy source, while chemotrophs rely on oxidizing chemical compounds. Further differentiation arises...
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"A designer diet layout for astronauts using a microbiome mediated approach."

Smriti Arora1, Samikshha Puri1, Nitika Bhambri1

  • 1Department of Allied Health Sciences, School of Health Sciences and Technology, University of Petroleum and Energy Studies (UPES), Energy Acres Building, Bidholi Dehradun, 248007 Uttarakhand, India.

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Space travel causes gut microbiota dysbiosis in astronauts. Diet interventions, including probiotics and prebiotics, can restore gut health and immune function during long-duration missions.

Keywords:
ISSNASAastronautdietdysbiosismicrobiome

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Area of Science:

  • Space microbiology
  • Human physiology
  • Astrobiology

Background:

  • Astronauts face stressors like microgravity and radiation during space missions.
  • These stressors disrupt the gut microbiota, leading to dysbiosis.
  • Gut dysbiosis is linked to metabolic, psychological, and immune disorders.

Purpose of the Study:

  • To review current research on astronaut gut microbiome dysbiosis.
  • To propose diet-mediated strategies for restoring astronaut health.
  • To explore personalized probiotic, prebiotic, and synbiotic interventions.

Main Methods:

  • Review of existing literature on astronaut gut microbiome studies.
  • Analysis of terrestrial analog models for spaceflight effects.
  • Exploration of microbial metabolite characterization for targeted interventions.

Main Results:

  • Spaceflight is associated with significant gut microbiota dysbiosis in astronauts.
  • This dysbiosis can lead to immune dysregulation.
  • Dietary interventions show promise in restoring gut homeostasis.

Conclusions:

  • Astronaut gut dysbiosis is a significant concern for long-term space missions.
  • Personalized probiotics, prebiotics, or synbiotics can mitigate space-associated dysbiosis.
  • Maintaining a balanced diet and exploring in-situ probiotic production are recommended.