Performance of the ATRIA Bleeding Score in Predicting the Risk of In-Hospital Bleeding in Patients with ST-Elevation
Fethi Yavuz1, Mehmet Kaplan2, Abdullah Yildirim3
1Department of Cardiology, Adıyaman University Training and Research Hospital, Adıyaman, Turkey.
The ATRIA bleeding score effectively predicts major bleeding in myocardial infarction (MI) patients undergoing percutaneous coronary intervention (PCI). This score is also valuable for ST-segment elevation MI (STEMI) and non-STEMI (NSTEMI) subgroups.
Area of Science:
- Cardiology
- Clinical Risk Stratification
- Hemorrhagic Complications
Background:
- Assessing bleeding risk in myocardial infarction (MI) patients is vital for prognosis.
- The Anticoagulation and Risk Factors in Atrial Fibrillation (ATRIA) score is validated for atrial fibrillation (AF) bleeding risk.
- The predictive value of the ATRIA score for bleeding post-percutaneous coronary intervention (PCI) in MI patients is unknown.
Purpose of the Study:
- To evaluate the predictive performance of the ATRIA bleeding score.
- To compare ATRIA with CRUSADE and ACUITY-HORIZONS bleeding scores.
- To assess predictive value in ST-segment elevation MI (STEMI) and non-STEMI (NSTEMI) patients.
Main Methods:
- Retrospective evaluation of 830 consecutive STEMI and NSTEMI patients undergoing PCI.
- Calculation of ATRIA, CRUSADE, and ACUITY-HORIZONS bleeding scores.
- Assessment of model discrimination using C-statistics.
Main Results:
- Major bleeding occurred in 6.3% of patients.
- All three bleeding scores (ATRIA, CRUSADE, ACUITY-HORIZONS) showed significant predictive value.
- Discriminatory abilities were similar: C-statistics 0.810 (ATRIA), 0.832 (CRUSADE), and 0.909 (ACUITY-HORIZONS).
- Predictive value was consistent across STEMI and NSTEMI subgroups.
Conclusions:
- The ATRIA bleeding score is a useful tool for predicting major in-hospital bleeding in MI patients.
- The ATRIA score maintains good predictive value in STEMI and NSTEMI subgroups.
- This study supports the utility of the ATRIA score beyond its original indication in AF patients.
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