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Published on: December 15, 2011
Severe childhood lichen planus pemphigoides after hepatitis A vaccination
M Lahouel1, A Aounallah1, S Mokni1
1Department of Dermatology Farhat Hached Hospital of Sousse Sousse Tunisia.
Background:
Lichen planus (LP) pemphigoides (LPP) is a very rare autoimmune bullous disorder, that is, exceptional in children.
Case Report:
We report a case of LP pemphigoides with severe cutaneous and mucosal involvement in an 8-year-old girl who consulted for multiple vesicular and bullous lesions associated with shiny erythematous-purple plaques. The eruption occurred 2 months after vaccination against hepatitis A virus. The diagnosis of LP pemphigoides was confirmed by histopathology and immunofluorescence examination. The patient received oral corticosteroid therapy with rapid improvement.
Conclusion:
To our knowledge, this is the first report of LPP following hepatitis A vaccination, among adults and children.
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