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Updated: Sep 20, 2025

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
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Cognitive Syndromes Associated With Movement Disorders.

Jennifer G Goldman, Samantha K Holden

    Continuum (Minneapolis, Minn.)
    |June 9, 2022
    PubMed
    Summary

    Recognizing cognitive syndromes in movement disorders is crucial for accurate diagnosis and management. Early screening aids in patient care and decision-making for conditions like Parkinson disease and Huntington disease.

    Area of Science:

    • Neurology
    • Neuroscience
    • Cognitive Science

    Background:

    • Cognitive and motor syndromes frequently coexist in neurodegenerative diseases.
    • Movement disorders like Parkinson disease, Huntington disease, and cerebellar syndromes often present with cognitive impairments.
    • Cognitive deficits typically impact attention, working memory, executive, and visuospatial functions.

    Purpose of the Study:

    • To review the recognition and management of cognitive syndromes in various movement disorders.
    • To highlight the importance of identifying cognitive changes for diagnosis and patient guidance.
    • To discuss the current limitations in pharmacologic treatments for cognitive impairment in these conditions.

    Main Methods:

    • Literature review of studies on cognitive syndromes in movement disorders.

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  • Analysis of cognitive symptom presentation in parkinsonism, chorea, ataxia, dystonia, and tremor.
  • Synthesis of current understanding of diagnosis and management strategies.

    • Main Results:

    • Cognitive syndromes are integral to the presentation of many movement disorders.
    • Specific patterns of cognitive deficits are observed, with some heterogeneity across disorders.
    • Effective screening and recognition are vital for comprehensive patient care.

    Conclusions:

    • Early identification of cognitive syndromes is essential for accurate diagnosis and management of movement disorders.
    • Pharmacological treatments for cognitive deficits in movement disorders are limited, necessitating further research.
    • A multidisciplinary team approach is crucial for optimal patient evaluation and care.