Unusual chromosome 7 aberrations in a case of eosinophilic myeloproliferative syndrome

A patient with myeloproliferative syndrome with marked eosinophilia was found to have unusual karyotypic abnormalities, including monosomy for the short arm and part of the long arm of chromosome #7 in cultured bone marrow cells. These abnormalities have never been reported previously. The role of chromosome #7 deletions in the genesis of leukemic disorders is discussed.