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Related Concept Videos

Proteins: Dietary Sources and Requirements01:28

Proteins: Dietary Sources and Requirements

653
Consuming animal-based products offers high-quality proteins that contain optimal levels and combinations of essential amino acids, crucial for tissue repair and growth. Foods like eggs, milk, fish, and most meats are a source of complete proteins. Legumes and cereals are abundant in proteins; however, they typically lack a full range of essential amino acids. As a result, they are considered incomplete protein sources. Some plant sources like soybeans, quinoa, and amaranth do contain complete...
653

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Related Experiment Video

Updated: Sep 20, 2025

Biological Samples Preparation for Speciation at Cryogenic Temperature using High-Resolution X-Ray Absorption Spectroscopy
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Dietary Selenium Across Species.

Xin Gen Lei1, Gerald F Combs2, Roger A Sunde3

  • 1Department of Animal Science, Cornell University, Ithaca, New York, USA;

Annual Review of Nutrition
|June 9, 2022
PubMed
Summary
This summary is machine-generated.

Selenium (Se) is an essential nutrient vital for health in animals and humans. This review covers Se discoveries, functions, diseases, and dietary needs across species, identifying research gaps.

Keywords:
animalhumannutritionseleniumselenoproteintoxicity

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Area of Science:

  • Nutritional biochemistry and molecular biology
  • Comparative animal and human physiology
  • Environmental science and food systems

Background:

  • Selenium (Se) was recognized as an essential trace element, crucial for various biological functions.
  • Understanding Se's role has evolved from deficiency diseases to molecular mechanisms involving selenoproteins.
  • Se metabolism and requirements vary significantly across different species, impacting health and disease.

Purpose of the Study:

  • To review the historical discoveries and current understanding of selenium's essentiality as a nutrient.
  • To analyze Se's metabolic functions, dietary sources, requirements, and impacts of intake across species.
  • To identify research needs for optimizing Se's application in food, nutrition, and health.

Main Methods:

  • Comprehensive literature review and synthesis of existing research on selenium.
  • Comparative analysis of selenogenomes and selenoproteomes in rodents, food animals, and humans.
  • Examination of metabolic pathways, dietary impacts, and Se recycling in food and ecosystems.

Main Results:

  • Detailed overview of Se's essentiality, linked to molecular mechanisms of Se-responsive diseases.
  • Comparative analysis highlights species-specific differences in Se utilization, requirements, and selenoprotein function.
  • Insights into Se metabolites, strategies for improving Se status, and its environmental cycling are presented.

Conclusions:

  • Selenium is indispensable for health, with diverse roles and requirements across species.
  • Further research is needed to fully elucidate Se's complex roles and optimize its use in nutrition and health.
  • Understanding Se's impact on health and disease requires a species-comparative and molecular approach.