Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inductively Coupled Plasma Atomic Emission Spectroscopy: Instrumentation01:26

Inductively Coupled Plasma Atomic Emission Spectroscopy: Instrumentation

307
Inductively coupled plasma (ICP) is the common plasma source used in atomic emission spectroscopy (AES), a technique that detects and analyzes various elements in a sample. This method is often called inductively coupled plasma atomic emission spectroscopy (ICP-AES).
There are three main types of inductively coupled plasma atomic emission spectroscopy  (ICP-AES) instruments: sequential, simultaneous multichannel, and Fourier transform instruments, with the latter being less commonly used....
307

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Coordinated immune activation following KRAS inhibition in syngeneic models reveals molecular pathways that potentiate and limit antitumor immunity.

Cancer immunology research·2026
Same author

SENSEI: A Search for Diurnal Modulation in Sub-GeV Dark Matter Scattering.

Physical review letters·2026
Same author

Prediction of vegetation indices from down-sampled hyperspectral data using machine learning: A novel framework for olive crop monitoring.

PloS one·2026
Same author

SENSEI at SNOLAB: Single-Electron Event Rate and Implications for Dark Matter.

Physical review letters·2025
Same author

Search for Reactor-Produced Millicharged Particles with Skipper-CCDs at the CONNIE and Atucha-II Experiments.

Physical review letters·2025
Same author

First Direct-Detection Results on Sub-GeV Dark Matter Using the SENSEI Detector at SNOLAB.

Physical review letters·2025

Related Experiment Video

Updated: Sep 20, 2025

Conducting Multiple Imaging Modes with One Fluorescence Microscope
08:32

Conducting Multiple Imaging Modes with One Fluorescence Microscope

Published on: October 28, 2018

10.0K

Multiplexed Readout for an Experiment with a Large Number of Channels Using Single-Electron Sensitivity Skipper-CCDs.

Claudio R Chavez1,2,3, Fernando Chierchie2, Miguel Sofo-Haro1,4

  • 1Fermi National Accelerator Laboratory, Batavia, IL 60510, USA.

Sensors (Basel, Switzerland)
|June 10, 2022
PubMed
Summary

This study introduces a multiplexed analog readout system for Skipper-CCDs, enabling precise single-electron counting. The design minimizes components and data requirements for high-channel-density particle detection experiments.

Keywords:
CCDsSkipper-CCDanalog charge pile-upmultiplexed readout electronicssub-electron countingultra low noise

More Related Videos

Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles
11:54

Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles

Published on: March 13, 2017

9.4K
Multiplexed Analysis of Retinal Gene Expression and Chromatin Accessibility Using scRNA-Seq and scATAC-Seq
06:24

Multiplexed Analysis of Retinal Gene Expression and Chromatin Accessibility Using scRNA-Seq and scATAC-Seq

Published on: March 12, 2021

3.7K

Related Experiment Videos

Last Updated: Sep 20, 2025

Conducting Multiple Imaging Modes with One Fluorescence Microscope
08:32

Conducting Multiple Imaging Modes with One Fluorescence Microscope

Published on: October 28, 2018

10.0K
Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles
11:54

Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles

Published on: March 13, 2017

9.4K
Multiplexed Analysis of Retinal Gene Expression and Chromatin Accessibility Using scRNA-Seq and scATAC-Seq
06:24

Multiplexed Analysis of Retinal Gene Expression and Chromatin Accessibility Using scRNA-Seq and scATAC-Seq

Published on: March 12, 2021

3.7K

Area of Science:

  • Physics
  • Electrical Engineering
  • Sensor Technology

Background:

  • Skipper-Charge-Coupled Devices (Skipper-CCDs) are advanced sensors capable of high-precision charge measurements.
  • Traditional readout electronics for Skipper-CCDs can be complex and data-intensive, posing challenges for high-channel-density applications.
  • Achieving single-electron counting requires minimizing noise and maximizing readout efficiency.

Purpose of the Study:

  • To implement a multiplexed analog readout electronics system for Skipper-CCDs.
  • To enable single-electron counting with non-destructive readout.
  • To optimize the system for high-channel-density experiments and low-threshold particle detection.

Main Methods:

  • Utilizing analog charge pile-up, sample and hold circuits, and analog multiplexing.
  • Designing a low-component-count system to maintain compatibility with dense sensor arrays.
  • Implementing a non-destructive readout strategy for Skipper-CCDs.
  • Achieving sub-electron noise-level operation.

Main Results:

  • Demonstrated single-electron counting capability using the multiplexed analog readout system.
  • Maintained sensor performance with sub-electron noise levels.
  • Achieved low-bandwidth data transfer, minimal analog-to-digital converters (ADCs), and low storage requirements.
  • Showcased zero added multiplexing time for simultaneous channel operation.
  • Presented experimental results from a 16-output stage sensor.

Conclusions:

  • The developed multiplexed analog readout system effectively enables single-electron counting with Skipper-CCDs.
  • The system's design is suitable for high-channel-density experiments, particularly in low-threshold particle detection.
  • The implementation offers a balance of high performance, low data requirements, and component efficiency.