Related Experiment Video
Updated: Sep 20, 2025

Murine Kidney Transplant Technique
Published on: October 20, 2015
COVID-19 in kidney transplant recipients; a DALMATIAN single-center experience
Tina Dogas1, Tonci Brkovic1,2, Ivana Novak1
1Division of Nephrology and Dialysis, University Hospital Centre Split, University of Split, School of Medicine, Split, Croatia.
Introduction:
We aimed to explore COVID-19 severity, complications, and outcome predictors in the Dalmatian population of kidney transplant recipients (KTRs).
Methods:
KTRs confirmed with acute COVID-19 infection until May 2021 were included and followed up for 6 months.
Results:
Out of 50 KTRs average aged 63 years, 36 (72%) were men. Nine (18%) KTRs had no pulmonary infiltration, and twenty-nine (58%) did not require oxygen supplementation. Bilateral pulmonary infiltrates had 29 (58%) while high-flow nasal cannula or mechanical ventilation required 8 (16%) KTRs. The mortality rate was 16%. Acute kidney injury developed in 18 (36%), and acute renal replacement therapy required 2 (4%) KTRs. Nine (18%) KTRs were subsequently rehospitalized. Chronic COVID-19 syndrome reported 23 (58%) KTRs.
Conclusions:
D-dimers were found to be the key prognostic factor of clinical complications, emphasizing the importance of underlying thrombotic microangiopathy. Optimal immunosuppressant adjusting in KTRs with acute COVID-19 infection remains to be clarified.
Related Concept Videos
Kidney Transplant I: Introduction
Kidney Transplant II: Surgical Procedure
Kidney Transplant III: Nursing Management
Acute Kidney Injury I: Introduction
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Acute Kidney Injury III: Clinical Manifestations

