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Isolation of Leukocytes from the Human Maternal-fetal Interface
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Complicated COVID-19 in pregnancy, maternal and neonatal outcomes: a case report

Mouna Gara1,2, Eya Sahraoui1, Wafa Dhouib3

  • 1Department of Anesthesia and Intensive Care "B", Center of Maternity and Neonatology, Fattouma Bourguiba University Teaching Hospital, Monastir, Tunisia.

The Pan African Medical Journal
|June 10, 2022
PubMed

Insights

This case study highlights severe COVID-19 in pregnancy, leading to critical illness and complications. Maternal COVID-19 can cause acute respiratory distress syndrome, coagulation issues, and preterm birth, with low risk of vertical transmission.

Area of Science:

  • Critical Care Medicine
  • Obstetrics and Gynecology
  • Infectious Diseases

Background:

  • Pregnancy presents unique physiological changes, potentially increasing susceptibility to severe outcomes from novel infectious diseases like COVID-19.
  • COVID-19 in pregnant individuals is linked to higher rates of hospitalization, ICU admission, and mechanical ventilation.
  • Immune and cardiorespiratory adaptations during pregnancy may exacerbate COVID-19 severity.

Observation:

  • A pregnant woman experienced critical respiratory failure due to COVID-19, requiring ICU admission and mechanical ventilation.
  • Post-childbirth, the mother developed disseminated intravascular coagulopathy and cardiopulmonary arrest.
  • Her preterm infant required NICU admission and intubation for bacterial pneumonia, recovering after 21 days.

Findings:

  • Maternal COVID-19 can precipitate acute respiratory distress syndrome (ARDS).
  • Coagulation dysfunction is a significant complication in severe COVID-19 during pregnancy.
  • Preterm delivery is a potential adverse outcome associated with maternal COVID-19 infection.
  • The risk of SARS-CoV-2 vertical transmission from mother to neonate appears to be very low.

Implications:

  • This case underscores the critical need for vigilant monitoring and management of pregnant women with COVID-19.
  • Understanding the impact of pregnancy on COVID-19 severity is crucial for clinical practice.
  • Further research is needed to elucidate the mechanisms behind severe COVID-19 manifestations in pregnancy and optimize neonatal care.

Keywords:
COVID-19case reportcoagulopathypregnancyrespiratory distress syndrome

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