Gliomatosis cerebri, report of a clinically diagnosed and histologically confirmed case

Pathological criteria for diffuse gliomatosis are clearly demarcated but its clinical diagnosis has always been hampered by the imaging techniques used. Although with the advent of CT scanning clinical possibilities were improved, isodense brain lesions are difficult to detect and in these cases the diagnosis gliomatosis cerebri can only be suspected from the clinical signs and the absence of radiological signs. We have studied a young patient with a peculiar clinical history, in whom comparison of the CT-scan and NMR scan yielded remarkable results. Our clinical diagnosis of (diffuse) gliomatosis was confirmed by biopsy.