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Ultrasonic Assessment of Myocardial Microstructure
Published on: January 14, 2014
Automated Diagnosis and Assessment of Cardiac Structural Alteration in Hypertension Ultrasound Images
U Raghavendra1, Joel Koh En Wei2, Anjan Gudigar1
1Department of Instrumentation and Control Engineering, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal 576104, India.
Insights
Hypertension (HTN) detection is improved using a computer-aided diagnosis (CAD) system analyzing ultrasound images. This method identifies early left ventricular changes in HTN patients, aiding cardiovascular disease prevention.
Area of Science:
- Cardiology
- Medical Imaging
- Computer-Aided Diagnosis
Background:
- Hypertension (HTN) is a significant risk factor for cardiovascular diseases, contributing to substantial mortality from heart disease and stroke.
- Prevalence of HTN is high in India and projected to increase, emphasizing the need for effective blood pressure control.
- Early detection of HTN-induced myocardial structural changes is crucial for managing cardiovascular risk.
Purpose of the Study:
- To develop and evaluate a multi-resolution analysis-based computer-aided diagnosis (CAD) system.
- To detect early left ventricular heart muscle changes associated with hypertension using ultrasound imaging.
- To assess the efficacy of LSDA and decision tree classification with contourlet and shearlet transforms for HTN detection.
Main Methods:
- Feature extraction from ultrasound imagery of the heart.
- Dimensionality reduction using locality sensitive discriminant analysis (LSDA).
- Classification using a decision tree model with contourlet and shearlet transform features, optimized to two key features.
Main Results:
- The developed CAD system effectively detected early HTN-induced left ventricular structural alterations.
- The combination of LSDA and decision tree classifier with specific transform features achieved high accuracy.
- The model demonstrated the potential for accurate diagnosis using a minimal set of features.
Conclusions:
- A multi-resolution analysis-based CAD system utilizing ultrasound imaging is effective for early detection of HTN-related cardiac changes.
- The system, employing LSDA and decision tree classification, offers a promising noninvasive tool for evaluating cardiac structural alterations in hypertensive patients.
- This standalone tool can be valuable for clinical applications in hospitals and polyclinics for managing hypertension.
Abstract:
Hypertension (HTN) is a major risk factor for cardiovascular diseases. At least 45% of deaths due to heart disease and 51% of deaths due to stroke are the result of hypertension. According to research on the prevalence and absolute burden of HTN in India, HTN positively correlated with age and was present in 20.6% of men and 20.9% of women. It was estimated that this trend will increase to 22.9% and 23.6% for men and women, respectively, by 2025. Controlling blood pressure is therefore important to lower both morbidity and mortality. Computer-aided diagnosis (CAD) is a noninvasive technique which can determine subtle myocardial structural changes at an early stage. In this work, we show how a multi-resolution analysis-based CAD system can be utilized for the detection of early HTN-induced left ventricular heart muscle changes with the help of ultrasound imaging. Firstly, features were extracted from the ultrasound imagery, and then the feature dimensions were reduced using a locality sensitive discriminant analysis (LSDA). The decision tree classifier with contourlet and shearlet transform features was later employed for improved performance and maximized accuracy using only two features. The developed model is applicable for the evaluation of cardiac structural alteration in HTN and can be used as a standalone tool in hospitals and polyclinics.
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