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Physico-chemical studies of resveratrol, methyl-jasmonate and cyclodextrin interactions: an approach to resveratrol
E Oliva1,2,3, D Mathiron2,3, E Bertaut4,3
1Laboratoire de Glycochimie des Antimicrobiens et des Agroressources, LG2A UMR 7378 CNRS, Université de Picardie Jules Verne 33 rue Saint-Leu 80039 Amiens France florence.pilard@u-picardie.fr.
Abstract:
trans-Resveratrol (RSV) is a natural phenolic molecule of the stilbene family known for its anti-oxidant properties in the field of nutraceuticals and cosmetics. Its production by grapevine cell suspensions is induced by the addition to the culture medium of elicitor compounds, methyl jasmonate (MeJA) and cyclodextrins (CDs). Physico-chemical studies were performed to understand the mechanism of action of CDs on this bioproduction of RSV. Inclusion complexes of RSV in CDs were first observed and then interactions with MeJA were identified using various analytical techniques such as UV and nuclear magnetic resonance (NMR) spectroscopies, mass spectrometry (MS) and isothermal titration calorimetry (ITC).
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