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Updated: Sep 20, 2025

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
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Gastroschisis Due to Maternal Exposure to Carbimazole in A Term Neonate

Suzan S Asfour1, Mountasser M Al-Mouqdad2

  • 1Clinical Pharmacy Department, King Saud Medical City, Riyadh, SAU.

Cureus
|June 10, 2022
PubMed

Pregnant women with hyperthyroidism need careful management, which is due to the increased risk of maternal and fetal complications. However, safe and effective therapies for hyperthyroidism during pregnancy remain limited. Carbimazole is an anti-thyroid agent and has been used to treat hyperthyroidism. Gastroschisis is a congenital severe abdominal birth defect of the fetus but its etiology remains unclear. Here, we present a case of a female term neonate who developed gastroschisis after being exposed to carbimazole in uteroduring the first and half of the second trimester.

Keywords:
carbimazolegastroschisishyperthyroidismneonateterm

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