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Closure of a Patent Foramen Ovale PFO: An Intervention Sequence
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Closure of a Patent Foramen Ovale PFO: An Intervention Sequence

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SA Heart consensus statement on closure of patent foramen ovale 2021

J Hitzeroth1, P van der Bijl2, F Michel3

  • 1Medical School, University of Cape Town, Cape Town, South Africa.

Cardiovascular Journal of Africa
|June 10, 2022
PubMed

Insights

Patent foramen ovale (PFO) is linked to several conditions, most seriously cryptogenic stroke. This guideline helps determine which patients benefit from PFO closure to prevent stroke.

Area of Science:

  • Cardiology
  • Neurology
  • Medical Guidelines

Background:

  • A patent foramen ovale (PFO) is an atrial septal defect present in adults.
  • PFO is associated with various clinical conditions, notably cryptogenic stroke, a major cause of morbidity.

Purpose of the Study:

  • To establish a clinical guideline for PFO closure in patients.
  • To identify patient populations who would most benefit from PFO closure procedures.

Main Methods:

  • This consensus statement synthesizes current evidence and expert opinion.
  • It focuses on risk stratification and patient selection for PFO closure.

Main Results:

  • Specific criteria for offering PFO closure are outlined.
  • The guideline addresses the balance between risks and benefits of closure.

Conclusions:

  • PFO closure is a viable option for select patients at high risk for cryptogenic stroke.
  • This guideline aims to standardize and optimize the decision-making process for PFO closure.

Keywords:
cryptogenic strokePFOPFO closurecryptogenic arterial embolismpatent foramen ovale

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