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Updated: Sep 20, 2025

Energy Dispersive X-ray Tomography for 3D Elemental Mapping of Individual Nanoparticles
Published on: July 5, 2016
Efficient full Monte Carlo modelling and multi-energy generative model development of an advanced X-ray device
Hermann Fuchs1, Lukas Zimmermann2, Niklas Reisz3
1Medical University of Vienna, Department of Radiation Oncology, Währinger Gürtel 18-20, 1090 Wien, Austria; MedAustron Ion Therapy Center, Marie-Curie-Straße 5, 2700 Wiener Neustadt, Austria.
Generative Adversarial Networks (GANs) offer a data-efficient alternative to phase space (PhS) files for Monte Carlo (MC) X-ray simulations. Conditional GANs provide superior data storage and computational efficiency for medical imaging applications.
Area of Science:
- Medical Physics
- Computational Imaging
- Radiological Sciences
Background:
- Monte Carlo (MC) simulations for X-ray imaging require significant data storage for phase space (PhS) files, especially for medical applications.
- Generative Adversarial Networks (GANs) have been introduced to address the data storage challenges associated with traditional PhS files.
Purpose of the Study:
- To compare the efficacy of phase space (PhS) files, traditional Generative Adversarial Networks (GANs), and conditional GANs as photon sources in MC simulations against experimental measurements.
- To evaluate the performance of a conditional GAN in modeling multiple X-ray energies within a single network.
Main Methods:
- Modeled an X-ray imaging system (ImagingRing) using GATE-RTion v1.0 for MC simulations.
- Implemented traditional and conditional GAN models for PhS generation.
- Measured half-value layers (HVLs), focal spot, and Heel effect for validation.
Main Results:
- MC simulations using both GAN approaches showed agreement with measured HVLs, focal spot, and Heel effect.
- The conditional GAN, with specific regularization, performed comparably to the traditional GAN.
- GANs demonstrated significant advantages over PhS files in data storage and computational overhead.
Conclusions:
- Conditional GANs offer a more efficient and flexible approach for generating X-ray sources in MC simulations compared to traditional PhS files.
- The developed conditional GAN enables energy interpolation, decoupling network training from specific X-ray energy requirements.
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