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Related Experiment Videos

Carbamazepine-induced acute cholangitis.

D Larrey, A Hadengue, D Pessayre

    Digestive Diseases and Sciences
    |May 1, 1987
    PubMed
    Summary

    Carbamazepine can cause acute cholangitis, a liver injury previously not linked to this drug. This finding suggests an immunoallergic mechanism for carbamazepine-induced liver damage.

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    Area of Science:

    • Hepatology
    • Clinical Pathology
    • Pharmacology

    Background:

    • Carbamazepine is a commonly prescribed anticonvulsant and mood-stabilizing drug.
    • Carbamazepine-induced liver injury (CILI) encompasses various histological patterns, including granuloma and hepatocellular necrosis.
    • Acute cholangitis has not been previously recognized as a manifestation of CILI.