[Pathology of primary non-Hodgkin's lymphoma of bone]

35 cases of primary non-Hodgkin's lymphoma (NHL) of bone are analysed. According to the diagnostic criteria of malignant lymphoma introduced at the National Conference on Lymphoma, they were divided into 3 groups: B cell derivative, T cell derivative and histiocytic derivative lymphomas. NHL of the bone was all of diffuse infiltration type, in which the incidence of T-cell and histiocytic derivative lymphomas was relatively frequent. X-ray changes and frequent complications of pathologic fracture in the tumor might be explained by the penetrating and osteolytic growth and direct morphologic osteolytic action of the tumor cells. But local fibrosis is more commonly found, on the basis of which reactive osseous hyperplasia is formed. Sometimes there are more macrophages and lymphocytes admixed around the tumor. It shows the immune reaction of the organism to the tumor.