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A novel technique to quantify aortic valve annulus deformation: A pilot study.

Theresa Holst^1,2, Johannes Petersen¹, Gerhard Adam³

¹Department of Cardiovascular Surgery, University Heart and Vascular Center UKE Hamburg, Hamburg, Germany.

Journal of Cardiac Surgery

|June 12, 2022

Summary

This summary is machine-generated.

Cardiac magnetic resonance (CMR)-derived strain can quantify aortic valve (AV) annulus deformation. Muscular AV annulus deformation is significantly altered in patients with severe aortic regurgitation compared to healthy controls.

Keywords:

aortic regurgitation aortic valve repair cardiac magnetic resonance imaging feature-tracking strain analysis

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Published on: February 23, 2020

Area of Science:

Cardiology
Medical Imaging
Biomechanical Analysis

Background:

Aortic valve (AV) annulus deformation is crucial for cardiac function.
Assessing AV annulus dynamics requires advanced imaging techniques.

Purpose of the Study:

To evaluate cardiac magnetic resonance (CMR)-derived strain for assessing aortic valve annulus deformation.
To compare AV annulus deformation during the cardiac cycle in patients with severe aortic regurgitation and healthy controls.

Main Methods:

Four patients with severe aortic regurgitation and seven healthy controls underwent CMR.
Longitudinal strain (LS) was assessed using CMR, focusing on the AV annulus.
Regional longitudinal strain (RLS) was calculated by averaging LS from muscular and fibrous AV annulus segments.

Main Results:

The muscular AV annulus showed significantly different deformation in patients with severe aortic regurgitation (median RLS: 4.18%) compared to controls (median RLS: -10.41%, p=0.024).
The fibrous AV annulus exhibited comparable deformational changes between the two groups.
CMR-derived strain successfully quantified AV annulus deformation.

Conclusions:

CMR-derived strain is a viable method for quantifying AV annulus deformation.
Altered regional longitudinal strain in the muscular AV annulus is indicative of severe aortic regurgitation.