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Nulligravida with Large Uterine Leiomyoma: A Case Report.
Sujata Maharjan1, Meena Thapa1, Manoj Pokhrel1
1Department of Obstetrics and Gynaecology, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal.
JNMA; Journal of the Nepal Medical Association
|June 12, 2022
Summary
This case report details a 36-year-old woman treated for a large uterine leiomyoma with hysterectomy. Preoperative gonadotropin-releasing hormone agonist therapy was used to reduce fibroid size.
Area of Science:
- Gynecology
- Oncology
Background:
- Uterine leiomyoma, the most common benign tumor of the female reproductive tract, affects women aged 30-50.
- Symptoms include abnormal uterine bleeding, pelvic pain, and pressure symptoms, often leading to hysterectomy.
Observation:
- A 36-year-old nulligravida presented with a large uterine leiomyoma (5.61 kg) without compression symptoms.
- The patient received a gonadotropin-releasing hormone agonist (leuprolide) preoperatively.
Findings:
- The patient underwent total abdominal hysterectomy with bilateral salpingectomy.
- The case highlights the use of gonadotropin-releasing hormone analogues in managing large uterine leiomyomas.
Implications:
- This case demonstrates a treatment approach for large uterine leiomyomas, even in asymptomatic patients.
- Preoperative GnRH analogue therapy can be a valuable tool for reducing uterine fibroid size before surgery.
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