Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sensation01:21

Sensation

814
Sensory receptors are specialized neurons that respond to specific types of external stimuli, initiating the process known as sensation. This occurs when sensory input, such as light entering the eye, is detected by these receptors, causing chemical changes in the cells of the retina. These cells then convert the sensory stimulus into action potentials that are transmitted to the central nervous system, a process termed transduction.
Absolute thresholds can quantify the sensitivity of sensory...
814
Graded Potential01:19

Graded Potential

4.8K
Graded potentials are localized fluctuations in the cell membrane's electrical charge, commonly found in the dendrites of neurons. The magnitude of these potential changes depends on the strength of the initiating stimulus. In a membrane at its resting potential, a graded potential signifies a voltage shift either above -70 mV or below -70 mV.
Graded potentials fall into two categories: depolarizing and hyperpolarizing. Depolarizing graded potentials typically occur when sodium (Na+) or...
4.8K
Heating and Cooling Curves02:44

Heating and Cooling Curves

24.2K
When a substance—isolated from its environment—is subjected to heat changes, corresponding changes in temperature and phase of the substance is observed; this is graphically represented by heating and cooling curves.
For instance, the addition of heat raises the temperature of a solid; the amount of heat absorbed depends on the heat capacity of the solid (q = mcsolidΔT). According to thermochemistry, the relation between the amount of heat absorbed or released by a substance, q, and its...
24.2K
Muscle Stimulation Frequency01:22

Muscle Stimulation Frequency

2.8K
The contraction strength of muscles is regulated by motor neurons, which modulate the frequency of action potentials dispatched to the motor units based on the body's requirements. This process of varying the muscle stimulation frequency allows muscles to contract with a force that is precisely tailored to the needs of the moment, whether lifting a feather or a heavy box.
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
2.8K
Desensitization and Tachyphylaxis01:20

Desensitization and Tachyphylaxis

2.3K
Tachyphylaxis is described as a rapid decrease in response to a drug after repeated or continuous administration of the same drug dose. It is a phenomenon where the body becomes less responsive to a particular substance or intervention over time, requiring higher doses or stronger interventions to achieve the same effect. It results from adaptive changes in the body's receptors, signaling pathways, or physiological processes that occur in response to prolonged exposure to a stimulus.
2.3K
Basic Continuous Time Signals01:22

Basic Continuous Time Signals

390
Basic continuous-time signals include the unit step function, unit impulse function, and unit ramp function, collectively referred to as singularity functions. Singularity functions are characterized by discontinuities or discontinuous derivatives.
The unit step function, denoted u(t), is zero for negative time values and one for positive time values, exhibiting a discontinuity at t=0. This function often represents abrupt changes, such as the step voltage introduced when turning a car's...
390

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Turning gold into lead: The troubling fate of the police drug diversion initiative.

Drug and alcohol review·2023
Same author

Following doctors' orders: informed consent in Australia.

The Australian law journal·1988
Same journal

The impact of drug decriminalization policy on mental health- and substance-related service utilization among people who use drugs with prior care in British Columbia.

The International journal on drug policy·2026
Same journal

Surveilled subjectivation: narratives of drug policing among people who use prohibited drugs in Sweden.

The International journal on drug policy·2026
Same journal

"Once I started going… I had this central wheel hub": Drivers of overdose prevention center engagement and connections to care in Rhode Island.

The International journal on drug policy·2026
Same journal

How many traffic fatalities can be attributed to cannabis each year in the US?

The International journal on drug policy·2026
Same journal

Value capture in the emerging medical cannabis global value chain: insights from South Africa.

The International journal on drug policy·2026
Same journal

"Just take it away from them and talk to them about it": exploring youth perspectives on and experiences with cannabis-related school discipline.

The International journal on drug policy·2026
See all related articles

Related Experiment Video

Updated: Sep 20, 2025

Estimating Vestibular Perceptual Thresholds Using a Six-Degree-Of-Freedom Motion Platform
06:31

Estimating Vestibular Perceptual Thresholds Using a Six-Degree-Of-Freedom Motion Platform

Published on: August 4, 2022

3.2K

Thresholds: First gradually, then suddenly?

Desmond Manderson1

  • 1ANU College of Law / College of Arts & Social Sciences The Australian National University, Australia.

The International Journal on Drug Policy
|June 12, 2022
PubMed
Summary
This summary is machine-generated.

This study examines drug quantity thresholds for distinguishing personal use from trafficking in Australia. It proposes a balanced approach, avoiding both rigid numbers and complete abandonment, to ensure fairness and harm reduction.

Keywords:
Burden of proofDecriminalisation of personal use of illicit drugsQuantifying measures of relative harmQuantitative thresholds

More Related Videos

Psychophysically-anchored, Robust Thresholding in Studying Pain-related Lateralization of Oscillatory Prestimulus Activity
07:28

Psychophysically-anchored, Robust Thresholding in Studying Pain-related Lateralization of Oscillatory Prestimulus Activity

Published on: January 21, 2017

7.1K
Psychophysical Tracking Method to Assess Taste Detection Thresholds in Children, Adolescents, and Adults: The Taste Detection Threshold TDT Test
08:52

Psychophysical Tracking Method to Assess Taste Detection Thresholds in Children, Adolescents, and Adults: The Taste Detection Threshold TDT Test

Published on: April 21, 2021

4.8K

Related Experiment Videos

Last Updated: Sep 20, 2025

Estimating Vestibular Perceptual Thresholds Using a Six-Degree-Of-Freedom Motion Platform
06:31

Estimating Vestibular Perceptual Thresholds Using a Six-Degree-Of-Freedom Motion Platform

Published on: August 4, 2022

3.2K
Psychophysically-anchored, Robust Thresholding in Studying Pain-related Lateralization of Oscillatory Prestimulus Activity
07:28

Psychophysically-anchored, Robust Thresholding in Studying Pain-related Lateralization of Oscillatory Prestimulus Activity

Published on: January 21, 2017

7.1K
Psychophysical Tracking Method to Assess Taste Detection Thresholds in Children, Adolescents, and Adults: The Taste Detection Threshold TDT Test
08:52

Psychophysical Tracking Method to Assess Taste Detection Thresholds in Children, Adolescents, and Adults: The Taste Detection Threshold TDT Test

Published on: April 21, 2021

4.8K

Area of Science:

  • Criminology
  • Public Health Policy
  • Drug Policy Analysis

Background:

  • Decriminalisation of illicit drugs is proposed in the Australian Capital Territory.
  • Quantitative thresholds for drug use present divergent global approaches and challenges.
  • Balancing quantitative measures against discretionary judgments is complex.

Purpose of the Study:

  • To explore the use of quantitative thresholds in distinguishing drug personal use from trafficking.
  • To evaluate the merits and implications of legally mandated drug quantities.
  • To propose a balanced approach to drug quantity thresholds that incorporates harm reduction principles.

Main Methods:

  • Literature review of global approaches to quantitative drug thresholds.
  • Analysis of the challenges in applying quantitative measures for drug law enforcement.
  • Critique of arguments for setting thresholds based on consumption and substance harm.

Main Results:

  • Quantitative thresholds for drug use present significant challenges and lead to divergent global practices.
  • Rigid application of quantitative thresholds risks injustice, while their abandonment risks discriminatory enforcement.
  • A 'middle way' approach, previously overlooked, is identified as a viable alternative.

Conclusions:

  • A nuanced approach to drug quantity thresholds is necessary, moving beyond simplistic numerical application.
  • Thresholds should be determined based on harm reduction principles and consumption patterns.
  • Further international dialogue on drug thresholds is crucial for equitable and effective drug policy.