Related Experiment Video
Updated: Sep 8, 2025
03:49
Application of Microwave Ablation in Laparoscopic Partial Splenectomy
Published on: November 15, 2024
270
[Splenic lymphoma, diagnosis and treatment]
Q Riller1, F Cohen-Aubart1, D Roos-Weil2
1Service de médecine interne 2, Centre national de référence maladies systémiques rares, hôpital Pitié-Salpêtrière, Sorbonne université, Assistance publique-Hôpitaux de Paris, 75013 Paris, France.
La Revue De Medecine Interne
|June 12, 2022
Summary
Splenic lymphoma, a rare non-Hodgkin lymphoma, presents diverse clinical and biological features. This review aids in diagnosing and differentiating these challenging hematological entities, including marginal zone lymphoma.
Area of Science:
- Hematology
- Oncology
- Pathology
Background:
- Splenic lymphoma is a rare group of hematological malignancies, predominantly of non-Hodgkin origin.
- Clinical presentations vary widely, from aggressive forms like hepato-splenic lymphoma to indolent types such as marginal zone lymphoma.
- Diagnosis and differentiation of splenic lymphoma entities can be challenging due to diverse clinical and biological manifestations.
Purpose of the Study:
- To review clinical and biological manifestations suggestive of splenic lymphoma.
- To propose a diagnostic work-up for suspected splenic lymphoma.
- To broaden the definition of splenic lymphoma to include cases presenting with splenomegaly and discuss differential diagnoses.
Main Methods:
- Literature review of clinical and biological presentations of splenic lymphoma.
- Analysis of diagnostic criteria and work-up strategies.
- Discussion of differential diagnoses for splenomegaly.
Main Results:
- Splenic lymphoma encompasses diverse hematological entities with varied presentations.
- Marginal zone lymphoma is the most common indolent form.
- Splenomegaly is a key indicator, necessitating consideration of splenic lymphoma in differential diagnoses.
Conclusions:
- Accurate diagnosis and differentiation of splenic lymphoma subtypes are crucial.
- A systematic diagnostic approach is proposed to manage these challenging conditions.
- Understanding the spectrum of splenic lymphoma, including presentations beyond exclusive splenic involvement, is important for effective patient management.
