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Retinal Pathophysiological Evaluation in a Rat Model
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Presumed retinal lead poisoning: a case report
Fatemeh Bazvand1, Zahra Mahdizad2
1Retina and Vitreous Service, Farabi Comprehensive Center of Excellence in Ophthalmology, Tehran University of Medical Sciences, Qazvin square, Tehran, 1336616351, Iran.
Purpose:
To describe a case of presumed retinal lead poisoning.
Methods:
Clinical examination, optical coherence tomography, fundus autofluorescence, fluorescein angiography, and electroretinography were used to study a 42-year-old male with the complaint of bilateral reduced vision following systemic lead poisoning.
Results:
The fundus examination showed venous tortuosity, as well as macular atrophy, and pigmentary changes in his both eyes. Optical coherence tomography revealed retinal thinning, outer retinal and retinal pigment epithelium atrophy, as well as foveal schitic changes. Blue autofluorescence showed moderately hypoautofluorescence in peripapillary area of both eyes. Fluorescein angiogram showed a leopard-like pattern of hypo- and hyperfluorescence in the posterior pole. Electroretinogram showed a moderate reduction in photopic and scotopic responses.
Conclusions:
The most probable diagnosis of this case is early onset retinal lead poisoning.
