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Updated: Sep 8, 2025

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Published on: February 25, 2013
Disease spreading modeling and analysis: a survey
Pietro Hiram Guzzi1, Francesco Petrizzelli2, Tommaso Mazza2
1Department of Surgical and Medical Sciences, Magna Graecia University, Catanzaro, 88110, Italy.
Motivation:
The control of the diffusion of diseases is a critical subject of a broad research area, which involves both clinical and political aspects. It makes wide use of computational tools, such as ordinary differential equations, stochastic simulation frameworks and graph theory, and interaction data, from molecular to social granularity levels, to model the ways diseases arise and spread. The coronavirus disease 2019 (COVID-19) is a perfect testbench example to show how these models may help avoid severe lockdown by suggesting, for instance, the best strategies of vaccine prioritization.
Results:
Here, we focus on and discuss some graph-based epidemiological models and show how their use may significantly improve the disease spreading control. We offer some examples related to the recent COVID-19 pandemic and discuss how to generalize them to other diseases.
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