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Updated: Sep 8, 2025

Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics
Published on: November 29, 2024
[Research progress on metabolomics of acute respiratory distress syndrome]
1Department of Pediatric Intensive Care Unit, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning, China. Corresponding author: Xu Wei,
Abstract:
Acute respiratory distress syndrome (ARDS) is a clinically and biologically heterogeneous disease. Given the heterogeneity of ARDS due to the wide range of etiological, clinical, and molecular manifestations, the current scientific consensus is that ARDS is not a single disease, but rather a set of diseases that require further research to properly classify and identify. Metabonomics, as a rapidly developing field of systems biology, has made many breakthroughs in science and medicine as an interdisciplinary platform. Metabonomics provides an important opportunity for the discovery and analysis of biomarkers in the diagnosis of ARDS, which is expected to reveal the biological process behind ARDS and show great potential in solving the heterogeneity and severity assessment of ARDS. This review focuses on the literature of ARDS metabonomics and summarizes the progress of ARDS metabonomics research and the main obstacles.
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