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Published on: February 13, 2021
Timing and mode of intervention for patients with left sided valvular heart disease: an individualized approach
Hannah McConkey1, Zhengang Zhao2, S Redwood1
1King's College London British Heart Foundation Centre of Excellence, The Rayne Institute, St. Thomas' Hospital Campus, London, United Kingdom, and the Department of Cardiology, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom.
Abstract:
Left sided valvular heart disease poses major impact on life and lifestyle. Medical therapy merely palliates chronic severe valve disease and once symptoms or haemodynamic sequelae appear, life expectancy is markedly truncated. In this article, we review the mechanisms of valve pathology, latest evidence in the quest for pharmacological options, means by which to predict deterioration, and standard and novel treatment options.
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