Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ultrasound II: Endoscopic Ultrasound and FibroScan01:25

Ultrasound II: Endoscopic Ultrasound and FibroScan

197
Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):
197

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Technical and Clinical Success of Endoscopic Hand-Suturing: A European Multicenter Study.

Endoscopy·2026
Same author

Inter and intra-observer agreement for the LST Classification in Large (>2cm) Colorectal Laterally Spreading Tumours.

The American journal of gastroenterology·2026
Same author

Sustainability in endoscopic medical congresses and courses: Position Statement from the European Society of Gastrointestinal Endoscopy and the European Society of Gastroenterology and Endoscopy Nurses and Associates.

Endoscopy·2026
Same author

Expert Endoscopist Agreement for Size Measurement of Large (> 2 cm) Colorectal Laterally Spreading Tumors: A Prospective Video-Based Study.

Digestive diseases and sciences·2026
Same author

Temporary interruption versus maintenance of anticoagulation in polypectomy of colorectal lesions: study protocol for a multicentre randomised non-inferiority clinical trial POLYPHEM.

BMJ open·2026
Same author

Accuracy of Size Measurement of Large (≥ 2 cm) Colorectal Laterally Spreading Tumours: A Prospective Video-Based Study.

Digestive diseases and sciences·2026

Related Experiment Video

Updated: Sep 8, 2025

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
06:46

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring

Published on: December 14, 2020

2.9K

Association between endoscopic pressure study integrated system (EPSIS) and high-resolution manometry.

Yusuke Fujiyoshi1, Haruhiro Inoue1, Yuto Shimamura1

  • 1Digestive Diseases Center, Showa University Koto Toyosu Hospital, Tokyo, Japan.

Endoscopy International Open
|June 13, 2022
PubMed
Summary

The endoscopic pressure study integrated system (EPSIS) effectively assesses lower esophageal sphincter (LES) function in gastroesophageal reflux disease (GERD) patients. This novel endoscopic tool correlates with high-resolution manometry findings, supporting its use in GERD diagnosis.

More Related Videos

Monitoring Lung Function with Electrical Impedance Tomography in the Intensive Care Unit
05:56

Monitoring Lung Function with Electrical Impedance Tomography in the Intensive Care Unit

Published on: September 6, 2024

3.3K
Contrast-Enhanced Subharmonic Aided Pressure Estimation SHAPE Using Ultrasound Imaging with a Focus on Identifying Portal Hypertension
06:20

Contrast-Enhanced Subharmonic Aided Pressure Estimation SHAPE Using Ultrasound Imaging with a Focus on Identifying Portal Hypertension

Published on: December 5, 2020

2.5K

Related Experiment Videos

Last Updated: Sep 8, 2025

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
06:46

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring

Published on: December 14, 2020

2.9K
Monitoring Lung Function with Electrical Impedance Tomography in the Intensive Care Unit
05:56

Monitoring Lung Function with Electrical Impedance Tomography in the Intensive Care Unit

Published on: September 6, 2024

3.3K
Contrast-Enhanced Subharmonic Aided Pressure Estimation SHAPE Using Ultrasound Imaging with a Focus on Identifying Portal Hypertension
06:20

Contrast-Enhanced Subharmonic Aided Pressure Estimation SHAPE Using Ultrasound Imaging with a Focus on Identifying Portal Hypertension

Published on: December 5, 2020

2.5K

Area of Science:

  • Gastroenterology
  • Diagnostic Endoscopy
  • Esophageal Physiology

Background:

  • Gastroesophageal reflux disease (GERD) diagnosis often relies on assessing the anti-reflux barrier.
  • The endoscopic pressure study integrated system (EPSIS) is a novel tool for evaluating intragastric pressure during endoscopy.
  • Its utility in assessing lower esophageal sphincter (LES) function requires further validation.

Purpose of the Study:

  • To evaluate the association between EPSIS parameters and LES function measured by high-resolution manometry (HRM).
  • To determine if EPSIS can serve as a reliable method for assessing LES function in GERD patients.

Main Methods:

  • A retrospective study included GERD patients who underwent endoscopy, pH-impedance monitoring, EPSIS, and HRM.
  • EPSIS parameters measured included pressure difference and pressure gradient during insufflation.
  • Basal LES pressure, end-respiratory LES pressure, and integrated relaxation pressure (IRP) were primary and secondary outcomes.

Main Results:

  • EPSIS pressure difference and pressure gradient significantly correlated with basal LES pressure (P=0.04).
  • Patients with an EPSIS GERD pattern exhibited significantly lower basal LES pressure, end-respiratory LES pressure, and IRP compared to those without.
  • These findings indicate a strong correlation between EPSIS measurements and established manometric measures of LES function.

Conclusions:

  • EPSIS demonstrates a close association with LES pressures determined by HRM.
  • The findings support EPSIS's capability to evaluate LES function during routine endoscopy.
  • EPSIS shows promise as a valuable diagnostic tool for GERD.