Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Asepsis01:28

Asepsis

The condition of being free from disease-causing living pathogens is asepsis. Aseptic techniques include a set of standard practices to achieve asepsis. An example is the regular environmental cleaning of all parts of the healthcare facility and hand hygiene at home before preparing or eating food. Medical and surgical asepsis in healthcare practice protects patients from harmful pathogens, minimizes the risk of contamination of susceptible sites, and reduces the risk of infection transmission.
Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration01:25

Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration

Hemoperfusion and hemofiltration are critical techniques in medical treatments to eliminate accumulated drugs, metabolites, and electrolytes from the bloodstream. These methods are particularly vital in cases of accidental poisoning and drug overdose.Hemoperfusion involves passing blood through an adsorbent material to remove unwanted substances. The main adsorbents used in hemoperfusion include activated charcoal and Amberlite resins. Activated charcoal can adsorb both polar and nonpolar...
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications01:25

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
Acute Inflammation III: Local and Systemic Effects01:25

Acute Inflammation III: Local and Systemic Effects

Acute inflammation produces a coordinated set of local and systemic changes that limit injury, eliminate pathogens, and initiate repair. These responses arise within minutes of infection, trauma, or chemical insult and are driven by vascular alterations and leukocyte-derived mediators. When the stimulus resolves, the reaction typically abates within days.Local EffectsAt the site of injury, arteriolar vasodilation increases blood flow, resulting in redness and warmth. Simultaneously, increased...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multiscale biased chemical space remodeling for developing APLNR agonists with anti-HFpEF efficacy.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Ligand recognition and G-protein coupling of trace amine receptor TAAR1.

Nature·2023
Same author

Mechanism of activation and biased signaling in complement receptor C5aR1.

Cell research·2023
Same author

Characterization of occult hepatitis B virus infection from blood donors in China.

Journal of clinical microbiology·2011
Same author

Cardioprotective effects of Glycyrrhiza uralensis extract against doxorubicin-induced toxicity.

International journal of toxicology·2011
Same author

Nanoscale Kirkendall effect for the synthesis of Bi2MoO6 boxes via a facile solution-phase method.

Nanoscale·2011

Related Experiment Video

Updated: Jun 9, 2026

Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury
07:03

Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury

Published on: February 15, 2022

1.5K

Blood purification for sepsis: an overview.

Ling Zhang1, Yuying Feng1, Ping Fu1

  • 1Division of Nephrology, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu 610041, China.

Precision Clinical Medicine
|June 13, 2022
PubMed
Summary

Sepsis management is advancing with extracorporeal blood purification techniques targeting infection and host response. This review explores progress, challenges in renal replacement therapy, and a strategy for clinical practice.

Keywords:
acute kidney injuryblood purificationsepsis

More Related Videos

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
07:30

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

Published on: June 15, 2019

10.1K
Purification of Platelets from Mouse Blood
05:41

Purification of Platelets from Mouse Blood

Published on: May 7, 2019

22.5K

Related Experiment Videos

Last Updated: Jun 9, 2026

Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury
07:03

Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury

Published on: February 15, 2022

1.5K
Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
07:30

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

Published on: June 15, 2019

10.1K
Purification of Platelets from Mouse Blood
05:41

Purification of Platelets from Mouse Blood

Published on: May 7, 2019

22.5K

Area of Science:

  • Critical Care Medicine
  • Nephrology
  • Infectious Diseases

Background:

  • Sepsis is a leading cause of intensive care unit mortality, characterized by organ failure and dysregulated host response to infection.
  • Extracorporeal blood purification technologies offer potential therapeutic avenues by addressing both pathogens and host immune mediators.
  • Current management strategies require optimization, particularly regarding renal replacement therapy in septic patients.

Purpose of the Study:

  • To review recent advancements in extracorporeal blood purification for sepsis management.
  • To identify and discuss unresolved questions concerning renal replacement therapy in septic patients.
  • To propose a clinical decision-making strategy for applying these technologies.

Main Methods:

  • Comprehensive literature search on extracorporeal blood purification techniques in sepsis.
  • Analysis of current evidence regarding efficacy and safety.
  • Synthesis of findings to inform clinical practice.

Main Results:

  • Extracorporeal therapies show promise in modulating inflammatory responses and removing sepsis-associated toxins.
  • Significant heterogeneity exists in study designs and outcomes, necessitating further research.
  • Gaps in understanding optimal timing, modality, and targets for renal replacement therapy in sepsis persist.

Conclusions:

  • Extracorporeal blood purification represents a developing field in sepsis management with potential benefits.
  • Further high-quality research is crucial to define the role and optimal application of renal replacement therapy in sepsis.
  • A structured approach can guide clinicians in selecting appropriate extracorporeal therapies for septic patients.