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Updated: Sep 8, 2025

Highly Sensitive and Rapid Fluorescence Detection with a Portable FRET Analyzer
Published on: October 1, 2016
A selective hybrid fluorescent sensor for fructose detection based on a phenylboronic acid and BODIPY-based
Gengo Kashiwazaki1, Ryo Watanabe1, Akihiro Nishikawa1
1Major in Advanced Bioscience, Graduate School of Agriculture, Kindai University 3327-204, Nakamachi Nara Nara 631-8505 Japan kitayama@nara.kindai.ac.jp.
Abstract:
Fructose is widely used in the food industry. However, it may be involved in diseases by generating harmful advanced glycation end-products. We have designed and synthesized a novel fluorescent probe for fructose detection by combining a phenylboronic acid group with a BODIPY-based hydrophobicity probe. This probe showed a linear fluorescence response to d-fructose concentration in the range of 100-1000 μM, with a detection limit of 32 μM, which is advantageous for the simple and sensitive determination of fructose.
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