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Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
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Peripunctal squamous cell carcinoma with canalicular infiltration
Richa Dharap Wagh1, Khaleel Machakuri1, Mohammad Javed Ali1
1Govindram Seksaria Institute of Dacryology, L.V. Prasad Eye Institute, Hyderabad, India.
Orbit (Amsterdam, Netherlands)
|June 13, 2022
Summary
Peripunctal squamous cell carcinomas invading the lacrimal system are rare. This case highlights successful surgical excision using intraoperative frozen section guidance for margin clearance in such complex eyelid tumors.
Area of Science:
- Ophthalmology
- Oncology
- Surgical Pathology
Background:
- Peripunctal squamous cell carcinoma (SCC) is a rare eyelid malignancy.
- Standard guidelines exist for eyelid tumor excision, but lacrimal system involvement presents unique challenges for margin clearance.
Observation:
- A rare case of SCC with secondary extension into the proximal lacrimal drainage system is presented.
- The tumor involved the eyelid margin and infiltrated the lacrimal canaliculi.
Findings:
- Surgical excision was performed with the assistance of intraoperative frozen section analysis.
- This technique allowed for precise identification of tumor margins and confirmation of complete resection.
Implications:
- Intraoperative frozen sections are crucial for achieving margin clearance in complex peripunctal SCC involving the lacrimal system.
- This approach can improve oncologic outcomes and preserve the function of the lacrimal drainage system.

