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Updated: Aug 18, 2026

Pseudofracture: An Acute Peripheral Tissue Trauma Model
Published on: April 18, 2011
[The effect of fracture and blood loss on the medullary circulation (author's transl)]
The blood flow of the cancellous bone of femoral head and diaphyseal bone marrow of the femur and humerus in dogs were measured by means of 133Xe and Hydrogen wash out methods. The blood flow rate of bone marrow in the femur counted from the Hydrogen wash out curves was 0,207 ml min-1 . g-1. Fracture and haemorrhagic hypotension decreased the blood flow rate in bone marrow. After bleeding there was an exponential relation between the arterial pressure and effective marrow flow or muscle flow. The relation between arterial and intramedullar pressure was exponential, but a linear correlation existed between the changes in marrow blood flow after haemorrhage and the changes in intramedullar pressure.
The blood flow of the cancellous bone of femoral head and diaphyseal bone marrow of the femur and humerus in dogs were measured by means of 133Xe and Hydrogen wash out methods. The blood flow rate of bone marrow in the femur counted from the Hydrogen wash out curves was 0,207 ml min-1 . g-1. Fracture and haemorrhagic hypotension decreased the blood flow rate in bone marrow. After bleeding there was an exponential relation between the arterial pressure and effective marrow flow or muscle flow. The relation between arterial and intramedullar pressure was exponential, but a linear correlation existed between the changes in marrow blood flow after haemorrhage and the changes in intramedullar pressure.
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