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Updated: Sep 8, 2025
Real-time Imaging of Single Engineered RNA Transcripts in Living Cells Using Ratiometric Bimolecular Beacons
Published on: August 6, 2014
Illuminating RNA biology through imaging
Phuong Le1,2,3, Noorsher Ahmed1,2,3,4, Gene W Yeo5,6,7,8
1Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.
Abstract:
RNA processing plays a central role in accurately transmitting genetic information into functional RNA and protein regulators. To fully appreciate the RNA life-cycle, tools to observe RNA with high spatial and temporal resolution are critical. Here we review recent advances in RNA imaging and highlight how they will propel the field of RNA biology. We discuss current trends in RNA imaging and their potential to elucidate unanswered questions in RNA biology.
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