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Updated: Sep 8, 2025

The Synthesis of RGD-functionalized Hydrogels as a Tool for Therapeutic Applications
Published on: October 7, 2016
Recent advances in the preparation, characterization, and food application of starch-based hydrogels
Congli Cui1, Yunzhu Jia1, Qi Sun1
1College of Food Science and Engineering, Qingdao Agricultural University, Qingdao, Shandong Province 266109, China.
Abstract:
Although synthetic polymer hydrogels have excellent mechanical properties, they are not easily degraded, are toxic, and easily cause environmental pollution. Therefore, starch-based hydrogels have attracted great interest due to their biodegradability, biocompatibility, and non-toxicity. First of all, this review describes in detail the preparation of starch-based hydrogels by physical retrogradation method and chemical crosslinking methods, as well as the intrinsic and extrinsic factors that affect the performance of the hydrogels. Moreover, the commonly used methods to characterize starch-based hydrogels and the properties of responsive (thermo-, pH-, and enzyme-responsive) starch-based hydrogels have also attracted wide attention from researchers. In addition, the applications of starch-based hydrogels in starch noodles, treatment of sewage from the food industry, and food bioactive ingredient carriers are discussed. Furthermore, prospects and future directions of starch-based hydrogels are discussed. We believe that this review provides a valuable reference for the efficient preparation and application of starch-based hydrogels.
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