Related Experiment Video
Updated: Sep 8, 2025

A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
Pulmonary Embolism (PE) in Transit in Heparin-Induced Thrombocytopenia (HIT) With Negative Serotonin-Release Assay
Tayyab Cheema1, Tri Kieu2, Mark Balek3
1Internal Medicine, Advocate Illinois Masonic Medical Center, Chicago, USA.
Abstract:
Pulmonary embolism (PE) is a potentially lethal condition, although frequently diagnosed, and is rarely associated with transit on initial presentation. Heparin-induced thrombocytopenia (HIT) can cause both arterial thrombus formation and venous thromboembolism. The two forms of HIT must be differentiated in order to guide management. We present a complex and unique case of PE in transit secondary to HIT diagnosed in a patient with a negative serotonin assay.
Related Concept Videos
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Pulmonary Embolism I: Introduction
Pulmonary Embolism III: Nursing Management
Anticoagulant Drugs: Low-Molecular-Weight Heparins
Venous Thrombosis III: Interprofessional Care
Drugs Affecting GI Tract Motility: Serotonin Receptor Agonists

