Related Experiment Video
Updated: Sep 8, 2025

Isolating Free Carbenes, their Mixed Dimers and Organic Radicals
Published on: April 19, 2019
Continuous Flow Technology as an Enabler for Innovative Transformations Exploiting Carbenes, Nitrenes, and Benzynes
Kian Donnelly1, Marcus Baumann1
1School of Chemistry, Science Centre South, University College Dublin, D04 N2E2 Dublin, Ireland.
Abstract:
Miniaturization offered by microreactors provides for superb reaction control as well as excellent heat and mass transfer. By performing chemical reactions in microreactors or tubular systems under continuous flow conditions, increased safety can be harnessed which allows exploitation of these technologies for the generation and immediate consumption of high-energy intermediates. This Synopsis demonstrates the use of flow technology to effectively exploit benzynes, carbenes, and nitrenes in synthetic chemistry programs.
Related Concept Videos
Reduction of Benzene to Cyclohexane: Catalytic Hydrogenation
Benzene to Phenol via Cumene: Hock Process
Electrophilic Aromatic Substitution: Nitration of Benzene
Electrophilic Aromatic Substitution: Fluorination and Iodination of Benzene
Electrophilic Aromatic Substitution: Chlorination and Bromination of Benzene
Electrophilic Aromatic Substitution: Friedel–Crafts Alkylation of Benzene

