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A Doxorubicin-Induced Murine Model of Dilated Cardiomyopathy In Vivo
Published on: May 16, 2020
[Dilated cardiomyopathy in a patient with Eosinophilic Granulomatosis with Polyangiitis (Churg Strauss)]
Julieta Lozita1, Judith Mailén Vicentín2, María Florencia Melgarejo Otarola3
1Sanatorio Allende, Servicio de Cardiología. Córdoba, Argentina.. julilozita@gmail.com.
Abstract:
Eosinophilic granulomatosis with polyangiitis, formerly known as Churg-Strauss Syndrome, is a rare pathology that belongs to the group of diseases characterized by necrotizing vasculitis of small and medium-sized systemic blood vessels. Symptomatic cardiovascular involvement occurs in 27% to 47% of Churg-Strauss cases, being one of the most serious manifestations. The diagnosis is usually confirmed with tissue biopsy showing eosinophil infiltration, but in selected cases with the recent inclusion of cardiac MRI, we can dispense with it. Early diagnosis is important because early treatment is usually associated with improvement in the condition.
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