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Updated: Sep 8, 2025

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
Published on: July 19, 2019
Newly Diagnosed Multiple Sclerosis Presenting as Brown-Séquard Syndrome: A Case Report
Shelby Hoebee1, Levi Howard2, James Komara2
1Creighton University Arizona Health Education Alliance, Valleywise Health, Department of Emergency Medicine, Phoenix, Arizona.
Introduction:
Brown-Séquard syndrome is a rare neurological disorder due to hemisection of the spinal cord that can occur from a variety of causes, most commonly trauma.
Case Report:
We present a case of a 25-year-old woman presenting with Brown-Séquard syndrome as her first clinical presentation of multiple sclerosis.
Conclusion:
This case highlights the need to have demyelinating disease on the differential as an exceedingly rare, but important, possible cause of Brown-Séquard syndrome.

