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Time to Surgery Does Not Impact Outcome in Pediatric Appendicitis
Mohamed Zouari1,2, Hana Ben Ameur1,2, Emna Krichen1,2
1Faculty of Medicine of Sfax, University of Sfax, Sfax, Tunisia.
Insights
Delaying appendectomy for pediatric acute appendicitis up to 24 hours is safe. This approach allows for conservative antibiotic treatment initially, especially for nighttime presentations, without impacting outcomes.
Area of Science:
- Pediatric Surgery
- Gastroenterology
Background:
- Acute appendicitis is common in children, leading to significant healthcare resource use.
- Optimal timing for appendectomy in pediatric cases remains debated.
Purpose of the Study:
- To investigate the link between time to appendectomy and patient outcomes in children.
- To evaluate the safety and feasibility of delayed appendectomy in pediatric acute appendicitis.
Main Methods:
- Retrospective analysis of 852 children under 14 undergoing appendectomy for suspected appendicitis.
- Patients were divided into early (<=8 hours) and delayed (>8 hours) appendectomy groups.
- Comparison of demographic, clinical, radiographic, peri-operative data, and outcomes between groups.
Main Results:
- No significant differences were observed in complicated appendicitis rates, post-operative complications, hospital stay duration, or 30-day readmission rates between early and delayed appendectomy groups.
- The study included 544 patients in the early group and 308 in the delayed group.
- The analysis covered an eight-year period.
Conclusions:
- Delayed appendectomy within 24 hours is a safe and feasible option for pediatric acute appendicitis.
- Conservative management with antibiotics may be suitable for initial treatment, particularly for nighttime presentations, enabling delayed surgery.
- This strategy can optimize surgical scheduling and resource allocation.
Abstract:
Despite the high prevalence of acute appendicitis in children and substantial resource utilization associated with this condition, no consensus has been reached on optimal timing for performing appendectomies. The aim of this study was to examine the association between time to appendectomy and outcomes and assess the feasibility of delayed appendectomy in children. We performed a retrospective analysis of all patients younger than 14 years of age undergoing an appendectomy for suspected appendicitis. We divided our patients into two groups based on whether their time to appendectomy was shorter or longer than eight hours: group A, early appendectomy and group B, delayed appendectomy. Then we compared the two study groups regarding demographic, clinical, and radiographic characteristics, peri-operative data, and outcomes. During the eight-year study period, a total of 1,141 patients underwent appendectomies. After applying exclusion criteria, 852 children were included: 544 (63.8%) in group A and 308 (36.2%) in group B. There were no differences in the rate of complicated appendicitis at exploration, post-operative complications, length of post-operative hospital stay, and 30-day re-admission rate between the two study groups. Our study demonstrated that delaying appendectomy within 24 hours of presentation is safe and feasible for pediatric acute appendicitis. Therefore, patients presenting during nighttime hours could be initially treated conservatively with antibiotic agents. This allows the surgeon to delay surgery to the following day.
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