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Related Concept Videos

Tissue Transplantation01:24

Tissue Transplantation

515
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
515
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
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Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

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Combined Islet and Kidney Xenotransplantation for Diabetic Nephropathy: Investigation of Pre-Vascularized Composite Grafts versus Sequential Islet-After-Kidney Transplantation in a Pig-to-Nonhuman Primate Model of Xenotransplantation.

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Kidney Transplantation in Two Highly Sensitized Candidates after CAR T-Cell Therapy.

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Renal Arterial Resistive Index Identifies Thrombotic Microangiopathy After Kidney Xenotransplantation in Pig-to-Baboon Model.

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Incidence of and Risk Factors for Delayed Engraftment after Post-Transplant Cyclophosphamide.

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Chimerism and a framework for clinical practice: A report from the Cellular Therapies Section Coordinating Committee (CTSCC) of Association for Advancement of Blood and Biotherapies (AABB).

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Major Histocompatibility Complex Class I Matching is Necessary but not Sufficient for Tolerance Induction to Vascularized Composite Allografts After Donor Hematopoietic Cell Transplantation.

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Related Experiment Video

Updated: Sep 8, 2025

Orthotopic Hind Limb Transplantation in the Mouse
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Transplantation Tolerance through Hematopoietic Chimerism

Thomas R Spitzer1, David H Sachs1

  • 1From the Departments of Medicine (T.R.S.) and Surgery (D.H.S.), Massachusetts General Hospital, Boston; and the Departments of Medicine and Surgery, Columbia University, New York (D.H.S.).

The New England Journal of Medicine
|June 15, 2022
PubMed
Summary

No abstract available in PubMed .

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