Related Experiment Video
Updated: Sep 8, 2025

Establishing a Competing Risk Regression Nomogram Model for Survival Data
Published on: October 23, 2020
Bivariate negative binomial regression model with excess zeros and right censoring: an application to Indonesian data
Seyed Ehsan Saffari1, John Carson Allen1
1Center for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.
We developed a new statistical model, the bivariate hurdle negative binomial (BHNB) regression, to better analyze health data with many zeros and extreme values. This model shows improved accuracy in predicting health outcomes compared to existing methods.
Area of Science:
- Biostatistics
- Statistical Modeling
- Epidemiology
Background:
- Count data with excess zeros and extreme values present challenges for standard statistical models.
- Existing bivariate models may not adequately capture the complexities of correlated health count data.
Purpose of the Study:
- To introduce and evaluate a novel bivariate hurdle negative binomial (BHNB) regression model.
- To address correlated bivariate count data characterized by excess zeros and few extreme observations.
- To improve the modeling of health-related count data, such as illness days.
Main Methods:
- Development of a bivariate hurdle negative binomial (BHNB) regression model incorporating right censoring.
- Parameter estimation using maximum likelihood with conjugate gradient optimization.
- Application to survey data on illness-related days missed and days spent in bed.
- Comparison with a right-censored bivariate negative binomial (BNB) model.
- Conducting a simulation study to assess model properties.
Main Results:
- The proposed BHNB model demonstrated superior goodness-of-fit for estimated frequencies compared to the BNB model.
- Simulation results support the utility and properties of the BHNB model for handling complex count data.
- The model effectively captures excess zeros and potential extreme values in bivariate count data.
Conclusions:
- The bivariate hurdle negative binomial (BHNB) regression model offers a robust approach for analyzing correlated bivariate count data with excess zeros.
- The BHNB model provides a better fit for health-related survey data than traditional bivariate negative binomial models.
- This methodology enhances the accuracy of statistical analyses in biostatistics and epidemiology.
Related Concept Videos
Censoring Survival Data
Truncation in Survival Analysis
Left truncation occurs when individuals who experienced the event of interest before a certain time are not included in the study. This is often due to a "delayed entry" into the study where only those who survive until a certain entry point are...
Parametric Survival Analysis: Weibull and Exponential Methods
Weibull Distribution
The Weibull distribution is a flexible model used in parametric survival analysis. It can handle both increasing and decreasing hazard rates, depending on its shape parameter...
Statistical Methods for Analyzing Epidemiological Data
Binomial Probability Distribution
The outcomes of a binomial experiment fit a binomial probability distribution. A statistical experiment can be classified as a binomial experiment if the following conditions are met:
There are a fixed number of trials. Think of trials as repetitions of an experiment. The letter n denotes the number of trials.
There are only two possible outcomes,...
Survival Tree
Building a Survival Tree
Constructing a...

