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Updated: Sep 7, 2025

Author Spotlight: Demonstrating Systematic Endobronchial Ultrasound to New Endoscopists
Published on: August 11, 2023
[Systemic nocardiosis with mediastinal lymph node involvement proven by endoscopic ultrasound]
S Storme1, R Bricca2, C M Gaillard1
1Service de pneumologie et de cancérologie thoracique, l'hôpital Nord Ouest, Villefranche sur Saône, France.
Introduction:
Systemic nocardiosis is an infectious disease that is rarely associated with mediastinal lymph nodes.
Case Report:
We report the case of a 72-year-old male patient treated with a high dose of oral corticosteroids for rheumatoid polyarthritis. This patient presented with rapid overall deterioration associated with mediastinal lymph nodes. Endobronchial ultrasound enabled us to establish a diagnosis of systemic nocardiosis. The patient recovered after having received suitable antibiotic treatment for four months.
Conclusion:
This work reports on a rare clinical presentation of systemic nocardiosis associated with mediastinal lymphadenopathies and highlights the key role of endobronchial ultrasound in diagnosing mediastinal lymph nodes, especially in differential diagnosis for lung cancer.
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