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Related Experiment Video

Updated: Sep 7, 2025

Intra-Operative Neural Monitoring of Thyroid Surgery in a Porcine Model
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Intra-Operative Neurophysiological Monitoring in Patients with Intraspinal Abnormalities Undergoing Posterior Spinal

Junyin Qiu1, Wanyou Liu1, Benlong Shi1

  • 1Division of Spine Surgery, Department of Orthopaedic Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.

Orthopaedic Surgery
|June 17, 2022
PubMed
Summary

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This summary is machine-generated.

Intraoperative neurophysiological monitoring (IONM) is effective for spinal fusion in patients with intraspinal abnormalities. Preoperative deficits and multiple abnormalities increase the risk of abnormal IONM results.

Area of Science:

  • Neurosurgery
  • Spinal Surgery
  • Neurophysiology

Background:

  • Intraspinal abnormalities complicate posterior spinal fusion.
  • Intraoperative neurophysiological monitoring (IONM) assesses neural integrity during surgery.
  • Understanding IONM in this context is crucial for patient safety.

Purpose of the Study:

  • To analyze IONM data in patients with intraspinal abnormalities undergoing posterior spinal fusion.
  • To identify how intraspinal abnormalities influence IONM outcomes.

Main Methods:

  • Retrospective review of 87 patients with severe kyphoscoliosis and intraspinal abnormalities (e.g., Chiari malformation, syringomyelia).
  • IONM data, including somatosensory evoked potentials (SSEP) and motor evoked potentials (MEP), were recorded.
Keywords:
Intraoperative neurophysiological monitoringIntraspinal abnormalityKyphoscoliosisMotor evoked potentialSomatosensory evoked potenti

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  • Analysis of risk factors for abnormal IONM results.

    • Main Results:

    • 59.8% of patients exhibited abnormal IONM data.
    • Preoperative neurological deficits and multiple intraspinal abnormalities were significant risk factors for abnormal IONM.
    • High sensitivity and specificity for both SSEP and MEP were observed.

    Conclusions:

    • IONM is a valuable tool for patients with intraspinal abnormalities undergoing posterior spinal fusion.
    • Identifying high-risk patients (preoperative deficits, multiple abnormalities) can guide monitoring strategies.