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Physiological Foundation of Stress01:24

Physiological Foundation of Stress

153
Stress triggers a coordinated physiological response involving the sympathetic nervous system (SNS) and the hypothalamic-pituitary-adrenal (HPA) axis. This dual activation ensures that the body is prepared for both immediate and prolonged stress management. The process begins with the perception of a stressor. This initial phase activates the SNS, leading to the rapid release of adrenaline (epinephrine) from the adrenal glands.
Role of the Sympathetic Nervous System
Adrenaline triggers the...
153
Introduction to Stress and Lifestyle01:27

Introduction to Stress and Lifestyle

168
Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
168
Psychological Responses to Stress01:20

Psychological Responses to Stress

94
Psychological responses to stress encompass the various cognitive and emotional reactions individuals experience when faced with challenging or threatening situations, such as a job loss. Prolonged exposure to stressors can disturb emotional balance, increasing negative emotions (e.g., anxiety and sadness) and diminishing positive emotions (e.g., joy and satisfaction). These persistent emotional shifts are associated with an increased risk of both physical illness and mental health issues, such...
94
Le Chatelier's Principle: Changing Concentration02:27

Le Chatelier's Principle: Changing Concentration

59.3K
A system at equilibrium is in a state of dynamic balance, with forward and reverse reactions taking place at equal rates. If an equilibrium system is subjected to a change in conditions that affects these reaction rates differently (a stress), then the rates are no longer equal and the system is not at equilibrium. The system will subsequently experience a net reaction in the direction of a greater rate (a shift) that will re-establish the equilibrium. This phenomenon is summarized by Le...
59.3K
Applications of Stress01:04

Applications of Stress

395
Consider a structure made of a boom and a rod designed to support a load. These two components are connected by a pin and stabilized by brackets and pins. The boom and the rod are detached from their supports to assess the different stresses imposed on this structure, and a free-body diagram is drawn. Then, all the forces applied, including the load acting on the structure, are identified. The reaction forces exerted on both the boom and the rod are computed using the equilibrium equations.
The...
395
Effects of Temperature on Free Energy02:11

Effects of Temperature on Free Energy

26.0K
The spontaneity of a process depends upon the temperature of the system. Phase transitions, for example, will proceed spontaneously in one direction or the other depending upon the temperature of the substance in question. Likewise, some chemical reactions can also exhibit temperature-dependent spontaneities. To illustrate this concept, the equation relating free energy change to the enthalpy and entropy changes for the process is considered:
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Related Experiment Video

Updated: Sep 7, 2025

Assessment of Stress Effects on Cognitive Flexibility using an Operant Strategy Shifting Paradigm
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Assessment of Stress Effects on Cognitive Flexibility using an Operant Strategy Shifting Paradigm

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How Stress Can Change Our Deepest Preferences: Stress Habituation Explained Using the Free Energy Principle.

Mattis Hartwig1,2, Anjali Bhat3, Achim Peters4

  • 1German Research Center for Artificial Intelligence (DFKI), Lübeck, Germany.

Frontiers in Psychology
|June 17, 2022
PubMed
Summary

Stress habituation, explained by the free energy principle, involves reducing the precision of goal preferences. This process helps protect against toxic stress but may increase acceptance of precarious conditions.

Keywords:
decision-makingfree energygoal prioritisationstressstress habituation

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Area of Science:

  • Neuroscience
  • Computational Psychiatry
  • Theoretical Biology

Background:

  • Stress habituation is a phenomenon where individuals show reduced responses to repeated stressors.
  • The underlying mechanisms of stress habituation are not fully understood.
  • The free energy principle provides a framework for understanding self-organizing systems, including the brain.

Purpose of the Study:

  • To explain and model stress habituation using the free energy principle.
  • To introduce 'habituation priors' within the decision-making process.
  • To demonstrate how goal preferences influence habituation.

Main Methods:

  • Incorporating habituation priors into an agent's decision-making model.
  • Utilizing goal priors representing agent preferences.
  • Illustrating agent behavior through two examples.

Main Results:

  • Stress habituation minimizes free energy by reducing the precision of goal preferences.
  • Reduced precision leads to acceptance of adverse states (e.g., lower social status, poverty).
  • This acceptance mechanism explains the attenuated stress response observed in habituation.

Conclusions:

  • The free energy principle offers a formal and generalizable account of stress habituation.
  • Habituation involves encoding goal priors in brain regions like the ventromedial prefrontal cortex.
  • While protective against toxic stress, habituation may increase susceptibility to precarious living conditions and conditions like type 2 diabetes mellitus.