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Maternal and Neonatal Prognostic Factors for Cardiorespiratory Events in Healthy Term Neonates During Early

Jesús Rodríguez-López1, Javier De la Cruz Bértolo2, Nadia Raquela García-Lara1

  • 1Department of Neonatology, Health Research Institute Imas12, 12 de Octubre University Hospital, Complutense University, Madrid, Spain.

Frontiers in Pediatrics
|June 17, 2022
PubMed

Insights

Cardiorespiratory events (CREs) are common during early skin-to-skin contact (ESSC) in healthy newborns. Maternal age, primiparity, BMI, and nighttime birth increase the risk of these events.

Area of Science:

  • Neonatal care
  • Perinatal health
  • Maternal-fetal medicine

Background:

  • Early skin-to-skin contact (ESSC) can lead to alterations in peripheral oxygen saturation (SpO2) and heart rate (HR).
  • Cardiorespiratory events (CREs) are a concern during this critical period for healthy term newborns (HTNs).

Purpose of the Study:

  • To determine the incidence of CREs during ESSC in HTNs.
  • To identify maternal and neonatal prognostic factors associated with the risk of CREs.

Main Methods:

  • Pooled analysis of a clinical trial cohort involving healthy mother-child dyads during ESSC.
  • Continuous monitoring of SpO2 and HR using pulse oximetry within 2 hours after birth.
  • Logistic regression models to analyze prognostic factors for CRE occurrence (defined as SpO2 <91% or HR <111 or >180 bpm).

Main Results:

  • 169 out of 254 (66.5%) neonates experienced at least one CRE.
  • Increased risk of CREs associated with maternal age ≥35 years (OR 2.21), primiparity (OR 1.96), gestational BMI >25 kg/m² (OR 1.92), and nighttime birth (OR 2.47).

Conclusions:

  • CREs are more frequent in neonates born during nighttime and to mothers who are first-time mothers, aged ≥35 years, or have a gestational BMI >25 kg/m².
  • These risk factors are identifiable during childbirth, enabling closer surveillance of high-risk neonates during ESSC.
Abstract

Keywords:
cardiorespiratory eventsearly skin-to-skin contacthealthy term newbornsoxygen desaturationoxygen saturation monitoringprognostic factorpulse oximetrysudden unexpected postnatal collapse (SUPC)

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