Related Experiment Video For FFPE
Updated: Sep 7, 2025
RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 11, 2014
Detection of high-risk HPV in FFPE specimens of various tumours using the BD Onclarity™ HPV Assay
Robert van der Geize1, Natalie Methorst2, Maarten Niemantsverdriet2
1Laboratorium Pathologie Oost Nederland (labPON), Boerhaavelaan 59, 7555 BB, Hengelo, the Netherlands.
Abstract:
Analysis of high-risk HPV status on formalin-fixed paraffin-embedded (FFPE) tissue material is valuable for cervical-, head and neck-, anogenital- and other types of cancer, but commercial HPV assays have been developed specifically for cervix swab cells. We evaluated the BD Onclarity™ HPV Assay for the detection of high-risk HPV on an assortment of relevant FFPE tissues with known HPV status. Detection of high-risk HPV types using the BD Onclarity™ HPV Assay in FFPE specimens was easy and accurate.
